Close Menu
  • Business
  • Technology
  • Gadgets
  • Digital Marketing
  • Social Media
  • Health
  • Lifestyle
  • Gaming
Facebook X (Twitter) Instagram
Tech Remarkable
  • Business
  • Technology
  • Gadgets
  • Digital Marketing
  • Social Media
  • Health
  • Lifestyle
  • Gaming
Tech Remarkable
Home » Preparation of Phenylmagnesium Bromide
Main

Preparation of Phenylmagnesium Bromide

Ethan FrankBy Ethan FrankFebruary 7, 2023No Comments3 Mins Read
Phenylmagnesium Bromide
Phenylmagnesium Bromide

Preparation of phenylmagnesium bromide

Phenylmagnesium Bromide: The formation of the Grignard reagent from bromobenzene and magnesium in ether, is difficult from the experimental point of view. For the preparation of phenylmagnesium bromide is necessary to follow the directions carefully, particularly in the matter of using completely dry reagents and dry apparatus. The provided description is used for the preparation of 0.15 mol phenylmagnesium bromide solution in ether.

The phenylmagnesium bromide is prepared in a 250 ml two-necked round-bottomed flask, fitted with an efficient reflux condenser connected with a calcium chloride drying tube and dropping funnel, which will be filled with the mixture of ether and bromobenzene. The flask, condenser and dropping funnel should be as DRY as possible.

The magnesium (3.9 grams or 0.16 mole of magnesium turnings) is placed in the two-necked round-bottomed flask, the calcium chloride tubes are attached directly to the flask, and the flask is heated gently by carefully brushing the bottom with a luminous flame.

The flask on cooling sucks in dry air through the calcium chloride. The reaction flask with magnesium is cooled to room temperature before proceeding! The calcium chloride drying tubes are removed from the flask and immediately the flask is connected with the condenser and dropping funnel (the top of the condenser and dropping funnel is connected with calcium chloride drying tube). The dropping funnel is filled with the mixture of 75 ml of dry ether and 17.7 ml (or 26.6 grams, 0.17 mole) of dry bromobenzene.

15 ml of this mixture are added dropwise to the reaction flask containing magnesium. There usually is no immediate change and it is necessary to start the reaction before adding further quantities of reagents. A very effective way of doing this is to add a small crystal of iodine and when this is done the liquid suddenly becomes slightly cloudy and ebullition commences.

When the initial reaction has been started the mixture of dry bromobenzene in ether is added dropwise at such rate that the ether boils gently from the heat of the reaction alone and without the application of external heating. This takes 25-30 minutes and when the reaction is partially complete the dropping funnel is replaced by the drying tube or stopper and the reaction mixture is gently refluxed for about one-half hour longer in order to complete the reaction.

The magnesium disintegrates and the solution acquires either a cloudy or a brownish appearance. The reaction is complete when there are only a few small remnants of unreacted metal. The solution should be used at once; it deteriorates on standing over night.

Experiments in Organic Chemistry, L. F. Fieser, 68-69, 1941

Phenylmagnesium Bromide Preparation of Phenylmagnesium Bromide What is Phenylmagnesium Bromide
Ethan Frank

Leave A Reply Cancel Reply

Latest Post

How to Handle Probate Disputes: Mediation and Legal Options

December 9, 2024

Protecting Our Children: The Importance of Child Custody Investigations

December 9, 2024

One of the greatest Relationship Software For 2024

August 3, 2024

Gloss Mail-order Brides: How To Find A Spouse Out of Poland? Simply by Rick Dawson

July 27, 2024

TechRemarkable

Embark on a journey of discovery through the intricate realm of cutting-edge innovation and digital wonders. Our tech website is your compass in the digital landscape, guiding you through the latest advancements, insights, and trends that shape the future. Contact us: [email protected]

Editor's Pick

Learn about How to Index Your URL in Google

February 8, 2023

As Grandes Caça-níqueis E Apostas Esportivas Por Dinheiro Rea

March 4, 2023

Glory Casino Online In Banglades

May 2, 2023

Subscribe to Updates

Get the latest creative news from Techremarkable about Technology, Business. Health, Gaming & LifeStyle etc.

© 2025 Tech Remarkable. All rights reserved.
  • About Us
  • Contact Us
  • Privacy Policy
  • Terms & conditions

Type above and press Enter to search. Press Esc to cancel.